Abstract
Background: The prelude to diabetes is prediabetes in what can be described as a continuum from normoglycemia through worsening dysglycemia. Prediabetes is defined specifically as impaired glucose tolerance and/or impaired fasting glucose. The problem increases when we consider that many of the atherogenic risk factors are already present in the prediabetic stage, years before the diagnosis of type 2 diabetes. Carotid intima–media thickness (CIMT) and its increase is associated with several cardiovascular risk factors and manifest cardiovascular diseases. CIMT is suggested to be an important biomarker of subclinical atherosclerosis.
Objective: (1) To study on the characteristics of carotid intima-media thickness and cardiovascular risk factors in study subjects. (2) To investigate the relationship between carotid intima-media thickness and cardiovascular risk factors in the study subjects.
Material and method: A cross-sectional study in 85 outpatients and inpatients at Hue Central Hospital.
Results: The percentage of CIMT <0.9 mm group is 63.5%, CIMT (0.9-1.5 mm) is 25.9% and CIMT >1.5 mm is 10.6%; Prehistoric includes: 2.4% blood glucose disorders, 36.5% hypertension, 21.2% smoking and 20% dyslipidemia. Increased waist circumference was 61.2%, overweight-obesity was 42.4%, hypertension was 57.6%, increased glucose was 90.6%, increased HbA1c was 95.3%, dyslipidemia was 91.8% and hs-CRP increase was 45.9%. Groups with a history of smoking, hypertension, and blood lipid disorders had a higher rate of increased CIMT than groups without (smoking, hypertension, lipid blood disorders); The factors age ≥60, smoking, hypertension, decreased HDL-C and increased hs-CRP are factors independently associated with increased CIMT.
Conclusion: The present study emphasizes on the role of CIMT measurement as a routine investigation among pre-diabetics for early recognition of atherosclerosis and cardiovascular risk reduction
| Published | 2025-04-24 | |
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| Issue | Vol. 15 No. 1 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.1.11 | |
| Keywords | độ dày lớp nội trung mạc động mạch cảnh, tiền đái tháo đường Carotid intima media thickness, prediabetes |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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