Abstract
Background: Quantitative hepatitis B surface antigen (qHBsAg) has been considered as a useful biomarker for assessing viral replication activity and monitoring disease progression in patients with chronic hepatitis B. Objective: To describe serum qHBsAg levels and investigate the association between qHBsAg, HBV DNA levels, and selected laboratory parameters in patients with chronic hepatitis B. Materials and Methods: A cross-sectional study was conducted on 56 patients with chronic hepatitis B at Hue University of Medicine and Pharmacy Hospital from June 2025 to January 2026. Serum qHBsAg levels were measured using an electrochemiluminescence immunoassay. Patients were categorized according to hepatitis B e antigen (HBeAg) status into HBeAg-positive (n = 31) and HBeAg-negative (n = 25) groups. Results: The median serum qHBsAg level was 3.35 log10 IU/mL (IQR: 2.55 - 4.11). Patients in the HBeAg-| Published | 2026-06-18 | |
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| Issue | Vol. 16 No. S-1 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.S-1.1 | |
| Keywords | qHBsAg, HBV DNA, HBeAg, viêm gan B mạn tính qHBsAg, HBV DNA, HBeAg, chronic hepatitis B |
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Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
Nguyen, T. H., Phan, T. M. P., Nguyen, V. T., Ngo, V. Q. T., Le, T. B. C., Tran, T. K. L., Pham, T. T., Tran, T. B. N., Truong, T. B. P., & Tran, X. C. (2026). Assessment of the association between serum HBsAg levels and selected laboratory parameters in patients with chronic hepatitis B. Hue Journal of Medicine and Pharmacy, 16(S-1), 15–23. https://doi.org/10.34071/jmp.2026.S-1.1