Abstract

Objectives: This study aimed to evaluate of the relationship between the sperm survival test (STT) and the results of intrauterine insemination (IUI-Intrauterine insemination). Materials and methods: In this cross-sectional descriptive study, infertile couples who were treated by IUI at the Center of Reproductive Endocrinology and Infertility, Hue University of Medicine and Pharmacy Hospital from January 2018 to April 2021, were enrolled. Their administrative information was recorded, clinical examination, semen analysis and sperm survival test were performed for all study participant. The results of IUI cycles were collected as biochemical pregnancy test and clinical pregnancy test. Results: In total of 162 infertile couples with 202 cycles of IUI, the rate of biochemical pregnancy was 19.8% and clinical pregnancy was 13.36%. The group of normal STT was 55.45% and the group of abnormal STT was 44.55%. In the group of normal STT, the rate of biochemical pregnancy and clinical pregnancy was 27.6% and 17.9%. It was significantly higher than the group abnormal STT, respectively, the rate of biochemical pregnancy and clinical pregnancy was 10% and 7.8% (respectively p=0.002 and p=0.036). In the biochemical pregnancy group, the percentage of sperm vitality at 0h, 24h and 48h was 89.18%, 61.95% and 21%, the percentage of sperm motility was 79.75%, 34.33% and 6%, that higher than the non-pregnant group (p<0.05). In the clinical pregnancy group, the percentage of sperm vitality at 24h and 48h was 61.63% and 21%, the percentage of sperm motility was 34.7% and 6%, that higher than that of the non-pregnant group (p<0.05). Conclusion: The normal STT group results in better IUI outcomes compared to those with abnormal STT. Furthermore, the biochemical and clinical pregnancies groups had higher sperm survival potential vitality and sperm motility than those in the non-pregnant group.