The neutrophil-to-lymphocyte ratios and platelet-to-lymphocyte ratios in systemic lupus erythematosus in Hue University of Medicine and Pharmacy Hospital

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CÁC SỐ TỪ 2011-2023
Tạp chí Y Dược Học

Abstract

Background: Systemic lupus erythematosus (SLE) is a chronic systemic inflammatory autoimmune disease and has various clinical manifestations affecting organ systems. It is characterized by the deposition of immune complexes due to widespread loss of immune tolerance to nuclear self-antigens, as well as excessive proinflammatory cytokine production. The neutrophil-to-lymphocyte ratios (NLR) and platelet-to- lymphocyte ratio (PLR) in SLE are often higher than in the normal population, which is significantly related to disease progression and is an indicator of monitoring disease activity. Therefore, the study was conducted with the aim of understanding the change of some hematological indexes in patients with SLE. Materials and method: The study was conducted on 51 patients with newly diagnosed SLE at the Department of General Internal Medicine - Endocrinology - Musculoskeletal and a control group of 30 healthy people who came to the hospital of Hue University of Medicine and Pharmacy from June 2022 to March 2023. Results:
https://doi.org/10.34071/jmp.2023.3.23
Published 2023-06-10
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Issue Vol. 13 No. 3 (2023)
Section Original Articles
DOI 10.34071/jmp.2023.3.23
Keywords Systemic lupus erythematosus, NLR, PLR Lupus ban đỏ hệ thống, NLR, PLR

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Hoang, T. A. T., Nguyen, D. D. N., Nguyen, H. T. V., Le, P. M. T., Ha, N. T. D., & Nguyen, T. T. (2023). The neutrophil-to-lymphocyte ratios and platelet-to-lymphocyte ratios in systemic lupus erythematosus in Hue University of Medicine and Pharmacy Hospital. Hue Journal of Medicine and Pharmacy, 13(3), 158–163. https://doi.org/10.34071/jmp.2023.3.23