Indexing
CÁC SỐ TỪ 2011-2023
Tạp chí Y Dược Học
Abstract
Background: Alpinia pinnanensis is commonly used in Vietnamese ethnomedicine for treating various ailments such as cough, fever, abdominal pain, flatulence and stomachaches. However, research on A. pinnanensis remains limited.
Objectives: This study was conducted to perform a preliminary phytochemical screening, quantify the total phenolic and flavonoid contents and assess the antioxidant potential of A. pinnanensis.
Materials and methods: The whole of A. pinnanensis was collected from A Luoi district, Thua Thien Hue province. Phytochemical analysis was conducted through specific chemical reactions. Total phenolic and flavonoid contents were quantified using the Folin-Ciocalteu and the aluminum chlorid assays, respectively. Antioxidant activity was assessed via the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) and 2,2-azino-bis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assays.
Results: Phytochemical analysis revealed the presence of flavonoids, coumarins, saponins and tannins. The aerial part extract showed higher total phenolic (132.94 ± 1.24 mg GAE/g) and flavonoid (13.50 ± 0.11 mg QE/g) contents compared to the underground part. Furthermore, the aerial part extract demonstrated significant antioxidant activity in both DPPH and ABTS radical scavenging assays with IC50 values of 19.03 ± 0.11 µg/mL and 2.63 ± 0.18 µg/mL, respectively.
Conclusion: This study provided the first detailed report on phytochemicals, total phenolic and flavonoid contents and antioxidant activity of A. pinnanensis, highlighting its potential for further exploration in pharmaceutical and neutraceutical applications.
| Published | 2026-08-25 | |
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| Issue | Vol. 16 No. 04 (2026) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2026.4.1614 | |
| Keywords | Alpinia pinnanensis, total phenolic, total flavonoid, DPPH, ABTS |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2026 Hue Journal of Medicine and Pharmacy
Chandimali N, Bak SG, Park EH, Lim HJ, Won YS, Kim EK, et al. Free radicals and their impact on health and antioxidant defenses: a review. Cell Death Discov. 2025;11(1):1-17.
Chibuye B, Singh IS, Ramasamy S, Maseka KK. Natural antioxidants: a comprehensive elucidation of their sources, mechanisms and applications in health. Next Res. 2024;1(2):1-21.
Hong TV, Tran DT, Luu TN, Doan VD. An overview of the chemical composition and biological activities of essential oils from Alpinia genus (Zingiberaceae). RSC Adv. 2021;11(60):37767-37783.
Youn I, Han AR, Piao D, Lee H, Kwak H, Lee Y, et al. Phytochemical and pharmacological properties of the genus Alpinia from 2016 to 2023. Nat Prod Rep. 2024;41(9):1346-1367.
Nguyen PH, Nguyen QB, Adhikari BS. Distribution of Alpinia (Zingiberaceae) and their use pattern in Vietnam. J Biodivers Endanger Species. 2014;2(2):1-5.
Flora of China: Flagellariaceae through Marantaceae. Beijing: Science Press; 2000. 24:344.
Phan MG, Phan TS, Matsunami K, Otsuka H. New diarylheptanoids from Alpinia pinnanensis. Chem Pharm Bull (Tokyo). 2005;53(10):1335-1337.
Le TH, Do ND, Tran DT, Tran TB, Ogunwande IA. Analysis of the volatile constituents of Alpinia pinnanensis. J Essent Oil Bear Plants. 2017;20(1):264-271.
Nguyen TT, Tran VC, Le DG, Tran TH, Nguyen TGA, Nguyen TV, et al. Rhizome essential oil of Alpinia pinnanensis from Vietnam: chemical composition and in vitro evaluation of antimicrobial and cytotoxic activities. Pharmacia. 2025;72:1-7.
Shaikh RJ, Patil MK. Qualitative tests for preliminary phytochemical screening: an overview. Int J Chem Stud. 2020;8(2):603-608.
Vala M, Maitreya B. Qualitative analysis, total phenol content (TPC) and total tannin content (TTC) by using different solvent for flower of Butea monosperma (Lam.) Taub. collected from Saurashtra region. J Pharmacogn Phytochem. 2019;8(3):2902-2906.
Pham TTH, Nguyen TBT, Nguyen TNT, Vo HK. Total phenolic, total flavonoid contents and antioxidant potential of common bean (Phaseolus vulgaris L.) in Vietnam. AIMS Agric Food. 2020;5(4):635-648.
Asekun OT, Okoh SO, Familoni OB, Afolayan AJ. Chemical profiles and antioxidant activity of essential oils extracted from the leaf and stem of Parkia biglobosa (Jacq) Benth. Res J Med Plants. 2013;7(2):82-91.
Dimitrina Z-D, Nedialkov P, Kitanov G. Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria. Pharmacogn Mag. 2010;6(22):74-78.
Dong JW, Cai L, Xing Y, Yu J, Ding ZT. Re-evaluation of ABTS•+ assay for total antioxidant capacity of natural products. Nat Prod Commun. 2015;10(12):2169-2172.
Nguyen DQP, Doan QT, Nguyen THT, Huynh VQ. Microscopic characteristics, total phenolic content and antioxidant activity of Alpinia breviligulata (Gagnep.) Gagnep. TNU J Sci Technol. 2024;229(13):218-225.
Aziz IM, Alfuraydi AA, Almarfadi OM, Aboul-Soud MAM, Alshememry AK, Alsaleh AN, et al. Phytochemical analysis, antioxidant, anticancer, and antibacterial potential of Alpinia galanga (L.) rhizome. Heliyon. 2024;10:1-16.
Sahoo S, Ghosh G, Das D, Nayak S. Phytochemical investigation and in vitro antioxidant activity of an indigenous medicinal plant Alpinia nigra B.L. Burtt. Asian Pac J Trop Biomed. 2013;3(11):871-876.
Chompoo J, Upadhyay A, Fukuta M, Tawata S. Effect of Alpinia zerumbet components on antioxidant and skin diseases-related enzymes. BMC Complement Altern Med. 2012;12:1-9.
Swain S, Tripathi P, Kavita G, Laxmi MNV, Subramani T. In vitro antioxidant and free radical scavenging activity of Alpinia calcarata: a novel underutilized crop in tropical island. J Pharmacogn Phytochem. 2020;9(5):243-248.