Abstract
Gut microbiota account for 90% of the human microbiota with a homologous and symbiotic relationship to ensure homeostasis. Intestinal dysbiosis (reduced Akkermansia muciniphila and Bacteroidetes, increased Firmicutes/Bacteroidetes ratio) is the beginning, plays a key role in the pathogenesis of hypertension, diabetes, dyslipidemia... is due to a decrease in short-chain fatty acids (SCFAs), indole; increased TMA, TMAO, LPS, BCAAs, serotonin; increased intestinal mucosal permeability and increased inflammation…Probiotic/ synbiotic as adjunctive therapy in the treatment/prevention of hypertension, diabetes as well as dyslipidemia at present and in the future. Proper diet and exercise combined with probiotic/synbiotic in addition to good control of blood pressure, blood glucose, blood fat and also anthropometric indicators
| Published | 2024-12-25 | |
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| Issue | Vol. 14 No. 7 (2024) | |
| Section | Reviews | |
| DOI | 10.34071/jmp.2024.7.1 | |
| Keywords | Gut microbiota, dysbiosis, short chain fatty acids (SCFAs), lipopolysaccharide (LPS), trimethylamine (TMA), trimethylamine N-Oxide (TMAO), branched-chain amino acids (BCAAs), probiotic, synbiotic, hypertension, diabetes, dyslipidemia. Khuẩn chí ruột, loạn khuẩn ruột, axit béo chuỗi ngắn (SCFAs), lipopolysaccharide (LPS), trimethylamine (TMA), trimethylamine N-Oxide (TMAO), acid amin chuỗi phân nhánh (Branched- Chain Amino Acid:BCAAs), probiotic, synbiotic, tăng huyết áp, đái tháo đường, rối loạn lipid máu. |
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