Abstract

Background: The Cardiovascular-kidney-metabolic Syndrome (CKMS) has still many aspects that have not been fully assessed in research. This study aimed on evaluation of medical history, clinical characteristics, biological features of CKMS, and the correlation among these features in acute stroke patients. Materials and method: Cross-sectional study, patients with non-communicable diseases were admitted to the hospital without intervention. Results: A study involving 88 acute stroke patients with CKMS revealed that 71.6% were in stage 4a, while 28.4% were in stage 4b. Regarding the number of diseases related to CKMS in the medical history, the proportions were as follows: The proportion of patients with a history of cardiovascular disease was 59.1%, dyslipidemia 22.7%, and diabetes 19.3%. Concurrent conditions included cardiovascular disease and diabetes at 14.8%, cardiovascular disease and dyslipidemia at 5.7%, dyslipidemia and diabetes at 5.7%, and all three conditions (cardiovascular disease, diabetes, and dyslipidemia) at 1.1%. The percentage of patients achieving the target LDL-C concentration in the study sample was 28.6%, and there was no statistically significant difference between stages 4a and 4b. Glomerular filtration rate (GFR) correlated with age and body mass index (BMI) (p<0.05; r=0.63 and r=0.45, respectively) and showed no correlation with TC, LDL-C, triglycerides (TG), and blood glucose levels. Conclusions: Patients with high cardiovascular risk but without renal impairment were predominant; no patients with chronic kidney disease were reported in their medical history. Cardiovascular disease had the highest prevalence, followed by dyslipidemia and diabetes. The proportion of patients achieving target LDL-C levels remained low.