Abstract
Back ground: Alcoholic cirrhosis is one of the leading causes of mortality in patients when complications arise. The ABIC score, which includes age, bilirubin levels, INR, and creatinine, has been recently proposed and demonstrated to have better short-term mortality prognostic ability than traditional scoring systems, particularly in patients with alcoholic hepatitis and cirrhosis. This study aims to assess the ABIC score and its prognostic value for certain complications and mortality in alcoholic cirrhosis patients during hospitalization, at 1 month, and at 3 months.
Methods and materials: A total of 117 decompensated alcoholic cirrhosis patients were admitted for treatment and monitored at Hue University of Medicine and Pharmacy Hospital and Hue Central Hospital. The ABIC score was assessed upon hospital admission, and the area under the ROC curve (AUC) was analyzed to predict cirrhosis-related events during hospitalization, at 1 month, and at 3 months.
Results: Patients’mean age of 52.83 ± 8.10 years, male/female: 114/3. The mean ABIC score of patients at hospital admission was 7.16 ± 0.98. The proportions of patients in the high-risk and intermediate-risk groups based on the ABIC score were 2.5% and 66.7%, respectively. The ABIC score had prognostic value for hepatorenal syndrome within 1 month, with an AUC of 0.780. Using a cutoff value of 7.78, it had a sensitivity of 80.0% and specificity of 77.7% (p = 0.034). Among the three time points for mortality risk assessment, the ABIC score was a significant predictor of mortality only at 3 months, with an AUC of 0.785 (p = 0.002), outperforming the CTP and MELD scores.
Conclusion: The ABIC score has good prognostic value for 3-month mortality. Additionally, it can predict the risk of hepatorenal syndrome within 1 month. Higher ABIC scores are associated with an increased risk of complications and mortality.
| Published | 2025-06-25 | |
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| Issue | Vol. 15 No. 3 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.3.16 | |
| Keywords | xơ gan do rượu, ABIC, tiên lượng Alcoholic Liver Cirrhosis, ABIC, Prognostic |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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