Abstract
Background and objectives: The genus Goniothalamus is one of the important genera of the Annonaceae family. However, research on G. tamirensis remains limited. This study provides a detailed analysis of the botanical characteristics and preliminary phytochemical screening of the stem and leaves of G. tamirensis. Additionally, it evaluates the potential of stem and leaf extracts from this species to inhibit nitric oxide (NO) production in RAW 264.7 cells. Materials and methods: The stems and leaves of G. tamirensis were collected in Phong Dien, Thua Thien Hue, in August 2024. The microscopic characteristics were analyzed using microscopy. Extraction was carried out via the Soxhlet method. The chemical components were identified through specific reactions. The anti-inflammatory activity was assessed using the NO production inhibition assay. Results: The anatomical features and powdered characteristics of the stems and leaves of G. tamirensis have been described. The chemical analysis reveals that both the leaves and stems contain alkaloids, fats, steroids, organic acids and reducing sugars. The extracts from these plant parts exhibit strong anti-inflammatory effects, primarily through the inhibition of NO production. Conclusion: This study is the first to report on the botanical characteristics and anti-inflammatory activity of the methanol extract from the stems and leaves of G. tamirensis.
| Published | 2025-06-25 | |
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| Issue | Vol. 15 No. 3 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.3.26 | |
| Keywords | Giác đế miên, đặc điểm thực vật, hoạt tính kháng viêm in vitro Goniothalamus tamirensis, anatomical characteristics, anti inflammatory in vitro |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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