Combination of thyroid ultrasound elastography and thyroid doppler ultrasound in the diagnosis of papillar thyroid cancer

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CÁC SỐ TỪ 2011-2023
Tạp chí Y Dược Học

Abstract

Objective: To determine the diagnostic value of papillary thyroid cancer through the combination of  thyroid ultrasound elastography and thyroid doppler ultrasound.

Patients and methods: 102 patients (50  patients with benign thyroid nodules and 52 patients with papillary thyroid cancer underwent thyroid  doppler ultrasound and thyroid ultrasound elastography from 4/2018 to 7/2020.

Results: In the patients  with papillary thyroid cancer, thyroid doppler ultrasound recorded the rate of TIRADS 4 as 5.8% and TIRADS 5  was 94.2% and had a diagnostic value for papillary thyroid cancer. Through thyroid ultrasound elastography,  the rate of Rago’s score 4 was 42.3%, Rago‘s score 5 was 40.4% and Rago’s score ≥ 4 was 82.7%. The strain  ratio at the cut-off point of 3.92 and the shear wave velocity at the cut-off point of 3.1 m/s had predictive  values for papillary thyroid cancer Combining the Rago‘s score 4 with the strain ratio (cut-off point of 3.17),  the 2D shear wave velocity (cut-off point of 2.9 m/s) both had a sensitivity of 100.0%. Combining thyroid  doppler ultrasound and thyroid ultrasound elastography recorded that when combining TIRADS score‘s 5  with strain ratio (cutoff point 3.8), shear wave velocity (cutoff point 3.05 m/s) had sensitivities of 95.2%  and 100.0%, respectively. When combining TIRADS 5 with Rago‘s score ≥ 4, the diagnostic value of thyroid  cancer with specificity and positive predictive value both increased to 100%.

Conclusion: Combination  of Thyroid ultrasound elastography and Thyroid Doppler ultrasound increases the accuracy in diagnosing  papillary thyroid cancer.

https://doi.org/10.34071/jmp.2025.5.5
Published 2025-09-30
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Issue Vol. 15 No. 5 (2025)
Section Original Articles
DOI 10.34071/jmp.2025.5.5
Keywords ung thư giáp thể nhú, siêu âm đàn hồi giáp, siêu âm doppler giáp, hệ thống TIRADS, thang điểm Rago, chỉ số siêu âm đàn hồi Papillary thyroid cancer, thyroid ultrasound elastography, thyroid doppler ultrasound, TIRADS (Thyroid Imaging Reporting and Data Systems), Rago‘s score, elastography index

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Nguyễn, H. T., Nguyễn, P. B. Q., & Nguyễn, T. H. (2025). Combination of thyroid ultrasound elastography and thyroid doppler ultrasound in the diagnosis of papillar thyroid cancer. Hue Journal of Medicine and Pharmacy, 15(5), 36–41. https://doi.org/10.34071/jmp.2025.5.5

Bùi Đặng Phương Chi, Lương Linh Hà, Đặng Văn Tuấn. Nghiên cứu giá trị của siêu âm đàn hồi mô trong chẩn đoán nhân tuyến giáp. Tạp chí Y Dược thực hành. 2016;175, 5, tr.54-60.

Đậu Thị Mỹ Hạnh. Nghiên cứu giá trị của siêu âm đàn hồi ARFI trong chẩn đoán các tổn thương dạng nốt tuyến giáp. Luận văn thạc sỹ của Bác sỹ nội trú. Trường Đại học Y Dược Huế. 2018.

Phạm Thị Diệu Hương, Nguyễn Minh Hải, Nguyễn Thị Hà. Nghiên cứu giá trị kỹ thuật siêu âm đàn hồi mô trong chẩn đoán ung thư tuyến giáp. Tạp chí Y Dược học Quân sự. 2017;Số 4, tr.159-165.

Ahmad Hafez Afifi , Walid Abdel Halim Abo Alwafa, Wael Mohamad Aly, Habashy Abdel Baset Alhammadi.Diagnostic accuracy of the combined use of conventional sonography and sonoelastography in differentiating benign and malignant solitary thyroid nodules. Alexandria Journal of Medicine. 2017;53(1), pp.21-30.

Ghobad Azizi, James Keller, Michelle Lewis, David Puett, Karly Rivenbark, Carl Malchoff. Performance of Elastography for the Evaluation of thyroid nodules: A prospective study. Thyroid. 2013;23(6), pp.734-740.

Baig F. N., Liu S. Y., Lam H. C., Yip S. P., Law H. K., Ying M. Shear wave elastography combining with conventional grey scale ultrasound improves the diagnostic accuracy in differentiating benign and malignant thyroid nodules. Appl. Sci. 2019;7(11), pp.1103.

Boucai L, Zafereo M, Cabanillas ME: Thyroid Cancer: A Review. JAMA. 2024;331(5):425–435. doi:10.1001/jama.2023.26348.

Vito Cantisani, Emanuele David, Hektor Grazhdani, Antonello Rubini, Maija Radzina, Christoph F Dietrich, et al. Prospective Evaluation of Semiquantitative Strain Ratio and Quantitative 2D Ultrasound Shear Wave Elastography (SWE) in Association with TIRADS Classification for Thyroid Nodule Characterization. Ultraschall Med. 2019;40(4), pp. 495-503.

Vito Cantisani, Hektor Grazhdani, Elena Drakonaki, Vito D’Andrea, Mattia Di Segni, Erton Kaleshi, et al. Strain US elastography for the Characterization of thyroid nodule: Advanges and limitation. Int J Endocrinol. 2015, 908575.

Dighe M. K. Elastography of Thyroid Masses. Ultrasound Clin. 2014;9(1), pp.13-24.

Dudea S. M., Botar-Jid C. Ultrasound elastography in thyroid disease. Med Ultrason. 2015;17(1), pp.74-96.

Kwak J. Y., Kim E. K. Ultrasound elastography for thyroid nodules: recent advances. Ultrasonography. 2014;33(2), pp.75-82.

Zhao Liu, Hui Jing, Xue Han, Hua Shao, Yi-Xin Sun, Qiu-Cheng Wang, Wen Cheng. Shear wave elastography combined with the thyroid imaging reporting and data system for malignancy risk stratification in thyroid nodules. Oncotarget. 2017;8(26), pp. 43406-43416.

Lobna A. M. Habib, Ahmed M. Abdrabou, Eman A. S. Geneidi et al. Role of ultrasound elastography in assessment of indeterminate thyroid nodules. The Egyptian Journal of Radiology and Nuclear Medicine. 2016;47(1), pp.141-147.

Hee Jung Moon, Ji Min Sung, Eun-Kyung Kim, Jung Hyun Yoon, Ji Hyun Youk, Jin Young Kwak. Diagnostic Performance of grayscale Us and elastography in solid Thyroid nodules. Radiology. 2012;262(3), pp.1002-1013.

Pedro Henrique de Marqui Moraes, Rosa Sigrist, Marcelo Straus Takahashi, Marcelo Schelini, Maria Cristina Chammas. Ultrasound elastography in the evaluation of thyroid nodules: evolution of a promising diagnostic tool for predicting the risk of malignancy. Radiol Bras. 2019;52(4), pp.247-253.

H Monpeyssen, J Tramalloni, S Poirée, O Hélénon, J-M Correas. Elastography of the thyroid. Diagn Interv Imaging. 2013;94(5):535-544.

Hussein Hassan Okasha, Mona Mansor, Nermine Sheriba, Maha Assem, Yasmine Abdelfattah, Omar A Ashoush, et al. Role of elastography strain ratio and TIRADS score in predicting malignant thyroid nodule. Arch Endocrinol Metab.2021;64(6), pp.735-742.

Stoian D., Bogdan T., Craina M., Craciunescu M., Timar R., & Schiller A. Elastography: A New Ultrasound Technique in Nodular Thyroid Pathology. Thyroid Cancer - Advances in Diagnosis and Therapy. Intech. 2016; 4, pp.86-110.

Zhao C. K., Xu H. X. Ultrasound elastography of the thyroid: principles and current status. Ultrasonography. 2019; 38(2), pp.106-124.