Abstract
Background: Mechanical biliary obstruction causes complications such as cholangitis, septic shock, and can lead to death. Endoscopic therapy aims to reduce biliary pressure, decrease the pressure gradient between the biliary tract and the duodenum at the sphincter of Oddi, and facilitate bile flow into the duodenum. Many studies have shown that temporary endoscopic biliary plastic stent placement yields good results in supporting treatment for mechanical biliary obstruction caused by biliary tumors or dificult common bile duct stones where second-stage stone removal is indicated.
Subjects and Methods: 41 patients diagnosed with mechanical biliary obstruction underwent endoscopic therapy with plastic biliary stent placement. The study was designed as a cross-sectional and observational.
Results: The technical success rate was 97.6% (40/41 patients), the stent occlusion rate was 2.4% (1/41 patients), and there were no cases of stent migration. Complications of the procedure included acute pancreatitis (4.9%), cholangitis (2.4%), and temporary bleeding requiring no re-intervention (7.3%). The mean VAS pain score showed a statistically significant change after stent placement (p < 0.05). In the group with biliary obstruction due to bile duct stones, clinical symptoms improved after treatment in over 80% of patients, and bilirubin levels decreased significantly (p < 0.05) after 1 week. In the group with biliary obstruction due to tumors, clinical symptoms improved after treatment ranging from 55% to 85%, and bilirubin levels decreased significantly at 1 week after biliary stent placement.
Conclusion: ERCP with plastic biliary stent placement demonstrates effectiveness and safety in cases of biliary obstruction due to tumors and stones. Temporary plastic biliary stent placement should be considered as a supportive treatment for mechanical biliary obstruction.
| Published | 2025-09-30 | |
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| Issue | Vol. 15 No. 5 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.5.21 | |
| Keywords | Nội soi mật tụy ngược dòng, tắc mật cơ học, stent nhựa đường mật Endoscopic Retrograde Cholangiopancreatography (ERCP), Mechanical Biliary Obstruction, Plastic Biliary Stent |
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Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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