Abstract
Objectives: To evaluate the effectiveness of Nifedipine in the treatment of pregnant women with threatened preterm labor with a gestational age of 22 - 36 weeks.
Methods: A cross-sectional descriptive study of 51 pregnant women diagnosed with threatened preterm labor at Da Nang Hospital for Women and Children from March 2022 to September 2023.
Results: The average age of pregnant women was 27.34 ± 6.37 years. The average gestational age was 30.15 ± 2.61 weeks. The rate of inhiniting uterine contractions was 82.4%. The rate of pregnancies prolonged ³ 48 hours and over one week in women diagnosed with TPL treated with Nifedipine was 82.4% and 78.5%, respectively. The treatment success rate in the group with uterine contraction frequency < 3 (95.0%) was higher than that in the group with uterine contraction frequency ≥ 3 (36.4%). The difference was statistically significant (p < 0.0001). There was a statistically significant difference in the rate of inhibition of uterine contractions by Nifedipine in the closed cervix group (89.6%) and 1 cm dilated cervix group (63.6%) compared to the 2cm dilated cervix group (28.6%) (p < 0.05). Headache was the most common adverse effect: 11.7%.
Conclusion: Nifedipine is highly effective and safe in the treatment of threatened preterm labor. The frequency of uterine contractions and the degree of cervical dilation are related to the effectiveness of inhibiting contractions.
| Published | 2025-09-30 | |
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| Issue | Vol. 15 No. 5 (2025) | |
| Section | Original Articles | |
| DOI | 10.34071/jmp.2025.5.22 | |
| Keywords | cơn go tử cung, dọa sinh non, sinh non uterine contractions, threatened premature birth, premature birth |
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Copyright (c) 2025 Hue Journal of Medicine and Pharmacy
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