Endovascular intervention in the treatment of acute middle cerebral artery occlusion at the M1 segment

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Abstract

Background: Stroke caused by middle cerebral artery (MCA) occlusion results in severe sequelae and a high risk of mortality. This study evaluates the roleof endovascular intervention and compares clinical and paraclinical characteristics of MCA occlusion at proximal and distal M1.

Materials and methods: Prospective study at Cho Ray Hospital from 01/2023 to 06/2024 on patients with MCA occlusion at M1 segment treated with endovascular intervention. Parameters assessed include lipid disorders, atrial fibrillation, mTICI score, recanalization time, NIHSS, and mRS at 90-day follow-up.

Results: Among 47 cases, successful recanalization (TICI 2b/3) was achieved in 93.62%, good clinical outcomes (mRS 0–2) in 51.06%, mortality was 21.28%, NIHSS averaged 17.72, and the mean recanalization time was 22.15 minutes. Distal M1 occlusion had a higher rate of atrial fibrillation compared to proximal M1 occlusion (56.52% vs. 12.50%), while proximal M1 occlusion had a higher prevalence of lipid disorders (80.95% vs. 50.00%).

Conclusion: Endovascular intervention for acute MCA occlusion at M1 segment achieves a high rate of successful recanalization and rapid recanalization time. Proximal M1 occlusion is associated with a higher prevalence of lipid disorders, whereas distal M1 occlusion is more frequently linked to atrial fibrillation.

https://doi.org/10.34071/jmp.2025.5.28
Published 2025-09-30
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Issue Vol. 15 No. 5 (2025)
Section Original Articles
DOI 10.34071/jmp.2025.5.28
Keywords đột quỵ, động mạch não giữa, can thiệp nội mạch stroke, middle cerebral artery, , endovascular intervention

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Nguyễn, H. N. T., Lê, V. P., & Nguyễn, T. T. (2025). Endovascular intervention in the treatment of acute middle cerebral artery occlusion at the M1 segment. Hue Journal of Medicine and Pharmacy, 15(5), 210–216. https://doi.org/10.34071/jmp.2025.5.28

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