Value of ALBI, PALBI classification in assessment of liver function in patients with hepatocellular carcinoma with cirrhosis at Nghe An Friendship General Hospital

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CÁC SỐ TỪ 2011-2023
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Abstract

Objectives: To assess the relationship between ALBI and PALBI grades with clinical and subclinical characteristics in patients with hepatocellular carcinoma (HCC) with cirrhosis at Nghe An Friendship General Hospital. Participants and Methods : A cross-sectional descriptive study on 82 patients diagnosed with cirrhosis and confirmed hepatocellular carcinoma at Nghe An General Friendship Hospital from January 2020 to June 2021. Results: The age group is mainly from 50 - 69 years old (63.4%); Male/Female ratio = 3.54/1; The rate of esophageal varices levels: non-varicose, 1,2,3 grade were 59.8%, 26.8%, 8.5% and 4.9%, respectively; The rate of Child-pugh A, B, C are: 73.2%, 20.7% and 6.1%, respectively; The rate of ALBI of grades 1,2,3 is 54.9%, 32.9% and 12.2% respectively; The PALBI-1 subgroup was the majority with 41.5%; PALBI-2,3 together accounted for 29.3%; There is a meaning correlation between ALBI, PALBI index and BCLC stage (Barcelona Clinic Liver Cancer); The threshold value of PALBI for diagnosis of esophageal varices is -2.219 with a sensitivity of 66.7% and a specificity of 83.7%. Conclusion: PALBI and ALBI grade are good, simple tools for assessing the stage, severity, and risk of esophageal varices in HCC patients with cirrhosis.
https://doi.org/10.34071/jmp.2022.5.16
Published 2022-10-30
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Issue Vol. 12 No. 5 (2022)
Section Original Articles
DOI 10.34071/jmp.2022.5.16
Keywords PALBI, ALBI, HCC, cirrhosis phân độ ALBI, PALBI, chức năng gan, ung thư biểu mô tế bào gan, xơ gan

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Nguyen, H. T., Tran, H. K., & Ho, D. T. A. (2022). Value of ALBI, PALBI classification in assessment of liver function in patients with hepatocellular carcinoma with cirrhosis at Nghe An Friendship General Hospital. Hue Journal of Medicine and Pharmacy, 12(5), 115–120. https://doi.org/10.34071/jmp.2022.5.16